Quality control (QC) in genomics workflows

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The challenges

Quality control is a crucial step in any genomics workflow to ensure the best outcomes from sequencing data.

While benchtop automation improves reliability and efficiency of processes in the lab, highly trained staff still need to conduct some manual work such as pipetting and moving consumables between instruments in the QC workflow. This can result in contamination, errors, limits to labs’ ability to scale and – most critically – means lab workers are locked into doing laborious tasks, day in and day out.

This is why we’ve developed a new approach to lab automation that enables true walkaway time; open, integrated automation.

Our solution: Open, integrated automation for QC steps

From 1388 manual touchpoints to 7 for 200 samples a day

This system, designed for a customer to enable scaling to 200 samples a day from 200 samples a week. The QC workflow consisted of a flowbot ONE liquid handler, a plate sealer, a plate peeler, an Agilent Microplate Centrifuge and a PHERAstar FSX plate reader from BMG LABTECH.

We calculated 1388 manual touchpoints for 200 samples, and through our platform of 4 smart benches, connected through 2 robotic arms and a magnetic transport layer, these touch points were brought down to 7.

The time needed for manual setup for 200 samples was reduced from 6 hours 10 minutes to just 15 minutes.

Is Automata right for my genomics lab?

Here are a few answers to some frequently asked questions

How can Automata help me if the requirements for my genomics workflow are different from the solutions you have on your website?

The solutions that we have showcased on our website for sample extraction, quality control, and library preparation are what we’ve built for specific customers with their needs in mind.

The beauty of the Automata platform is that we are not locked down and are vendor agnostic. We can integrate third party devices, and propose a solution for your lab based on your needs and the problems you are trying to solve.

My lab struggles with certain steps in the workflow. Does Automata’s integrated automation mean my solution needs to be multiple steps?

We create solutions for genomics workflows that can start with integrating laboratory equipment specific workflow steps (like workcells for library preparation, or quality control) to reduce manual steps, and save time.

Alternatively, we can also integrate multiple workcells together to combine entire workflows depending on the needs of your lab. The journey to automation can take time, so we can start where you would like to start and grow as your labs grow. We understand that labs also change the instruments they use, so we can always adapt the layouts of our platform as your needs change.

Are the instruments in my lab compatible with the Automata solution?

We have worked with many vendors and have a list of instruments that we have integrated with.

If we haven’t already integrated the instruments in your lab, we will work with you to find a solution to be able to do so, as well as suggesting instruments to fill any gaps.

How will Automata bring open, integrated automation to my lab?

If you are interested in our solution, get in touch with us!

We will visit your lab to understand your SOPs and pain points and work with you to estimate how best to optimise your workflow.

We will then work with existing automation to integrate it both physically and digitally, while suggesting solutions for any automation gaps to truly bring hands-free workflows to your lab.

Get in touch and find out how we can help your lab automate